A company created a disaster recovery site in a different AWS Region. The company needs to transfer large amounts of data periodically between NFS file systems in the two Regions. Which solution meets these requirements with the least operational overhead?

AWS DataSync is the most suitable solution because it is designed for online data transfer between on-premises storage and AWS, or between AWS storage services, including NFS file systems. It automates and accelerates data transfer, handles network interruptions, and provides end-to-end data integrity verification, significantly reducing operational overhead for periodic large-scale transfers. AWS Snowball devices are for offline data transfer of extremely large datasets (petabytes to exabytes) and are not ideal for periodic online transfers. Setting up an SFTP server on Amazon EC2 would require manual setup, configuration, and management of the server, increasing operational overhead and complexity compared to DataSync. AWS Database Migration Service (AWS DMS) is specifically for migrating databases, not general-purpose file system data.