An application running on Amazon EC2 instances needs to access an Amazon S3 bucket without traffic traversing the internet. How should a solutions architect configure access to meet this requirement?

Setting up a gateway VPC endpoint for Amazon S3 in the VPC is the correct solution because it allows EC2 instances to access S3 buckets privately, without traffic traversing the public internet. This enhances security and reduces data transfer costs. A private hosted zone with Route 53 is used for custom domain name resolution within a VPC, not for private S3 access. Configuring EC2 instances to use a NAT gateway would route traffic through the internet, which violates the requirement. An AWS Site-to-Site VPN connection is for connecting an on-premises network to a VPC, not for direct VPC to S3 private access.